CAIRO (AP) — An Israeli airstrike killed the prime minister of the Houthi rebel-controlled government in Yemen's capital Sanaa,the Houthissaid Saturday. He was the most senior Houthi official killed in the Israeli-U.S. campaign against the Iranian-backed rebels. Ahmed al-Rahawi was killedin a Thursday strike in Sanaaalong with a number of ministers, the rebels said in a statement. Other ministers and officials were wounded, the statement added without providing further details. The premier was targeted along with other members of his Houthi-controlled government during a "routine workshop held by the government to evaluate its activities and performance over the past year," the Houthi statement said. Thursday's Israeli strike took place as the rebel-owned television station was broadcasting a speech by Abdul Malik al-Houthi, the secretive leader of the rebel group in which he was sharing updates on the latest Gaza developments and vowing retaliation against Israel. Senior Houthi officials used to gather to watch al-Houthi's prerecorded speeches. Al-Rahawi wasn't part of the inner circle around Abdul Malik al-Houthi that runs the military and strategic affairs of the group. His government, like the previous ones, was tasked with running the day-to-day civilian affairs in Sanaa and other Houthi-held areas. The strike that killed the prime minister targeted a meeting for Houthi leaders in a villa in Beit Baws, an ancient village in southern Sanaa, three tribal leaders told The Associated Press. They spoke on condition of anonymity because they feared repercussions. On Thursday, the Israeli military said that it "precisely struck a Houthi terrorist regime military target in the area of Sanaa in Yemen." The military had no immediate comment on Saturday's announcement of the prime minister's killing. "Yemen endures a lot for the victory of the Palestinian people," al-Rahawi said followingan Israeli strike last weekthat struck an oil facility owned by the country's main oil company, which is controlled by the rebels in Sanaa as well as a power plant. The Aug. 24 strike came three days after the Houthis launched a ballistic missile toward Israel that its military described as the first cluster bomb the rebels had launched at it since 2023. The prime minister hailed from the southern province of Abyan, and was an ally toformer Yemeni President Ali Abdullah Saleh.He allied himself with the Houthis when the rebels overran Sanaa, and much of the north and center of the country in 2014, initiating the country's long-running civil war. He was appointed as prime minister in August 2024. Al-Rahawi is the most senior Houthi official to be killed since the United States and Israel began their air and naval campaign in response to the rebels' missile and drone attacks on Israel andon ships in the Red Sea. The U.S. and Israeli strikes killed dozens of people. One U.S. strike in April hit a prison holding African migrants in the northern Sadaa province,killing at least 68 people and wounding 47 others. Ahmed Nagi, a senior Yemen analyst with the Crisis Group International, a Brussels-based think-tank, called the killing of the Houthi prime minister a "serious setback" for the rebels. He said the escalation marks an Israeli shift from striking the rebels' infrastructure to targeting their leaders, including senior military figures, which "poses a greater threat to their command structure." TheHouthislaunched a campaign targeting ships in response tothe Israel-Hamas war in the Gaza Strip, saying they were doing so in solidarity with the Palestinians. Their attacks over the past two years have upendedshipping in the Red Sea, through which about $1 trillion of goods pass each year. In May, theTrumpadministrationannounced a deal with the Houthisto end the airstrikes in return for an end to attacks on shipping. The rebels, however, said the agreement did not include halting attacks on targets it believed were aligned with Israel.